George Mason University

Computational Hemodynamics Lab



Projects


Grant: NIH R21 NS094780
Dates: 09/15/2015 - 08/31/2018
Title: Improved evaluation of PCOM aneurysms: angio-architectures, hemodynamics and shape
Info: The objective of this project is to identify angio-architecture and aneurysm characteristics that distinguish between ruptured and unruptured PCOM aneurysms and use this information to better assess rupture risk
Data Sharing: The vascular models created as part of this project are available upon request. (Email the PI, Prof. Juan R. Cebral (jcebral@gmu.edu) to request the models).
The models are described in Chung BJ, Doddasomayajula R, Mut F, Detmer F, Pritz M, Hamzei-Sichani F, Brijikjiki W, Kallmes D, Jimenez C, Putman C, Cebral JR, Angioarchitectures and hemodynamics characteristics of posterior communicating artery aneurysms and their association with rupture status, AJNR, 38(11): 2111-2118, 2017 (DOI: 10.3147/ajnr.A5358).

Grant: NIH R01 NS076491
Dates: 09/01/2016 - 08/31/2021
Co-PIs: Dr. Ramanathan Kadirvel, Dr. David Kallmes - Mayo Clinic
Title: Computational and Biological Approach to Flow Diversion
Info: The major goal of this project is to model the hemodynamic alteration produced by flow diverting devices on animal models of cerebral aneurysms and relate them to long term aneurysm occlusion rates
Data Sharing: The vascular models created as part of this project will be made available upon request. (Email the PI, Prof. Juan R. Cebral (jcebral@gmu.edu) to request the models).

Grant: NIH R01 NS076491
Dates: 09/01/2016 - 08/31/2021
Co-PIs: Prof. Anne Robertson - University of Pittsburgh
Title: Improving cerebral aneurysm risk assessment through understanding wall vulnerability and failure modes
Info: The objective of this project is to connect flow conditions to wall structure and strength in cerebral aneurysms using resected tissue samples and computational modeling, and use this information to identify unruptured aneurysms at risk of rupture
Data Sharing: The vascular models created as part of this project will be made available upon request. (Email the PI, Prof. Juan R. Cebral (jcebral@gmu.edu) to request the models).