George Mason University

Research Gallery


Hemodynamics

hemo

The purpose of this research was to develop methods for image-based patient-specific computational fluid dynamics modeling of arterial hemodynamics, and to apply these methods to study vascular diseases for improving patient management.


Cerebral Aneurysms

aneu

The purpose of this research was to investigate possible relationships between aneurysmal hemodynamics and clinical events such as rupture. The objective is to improve patient evaluation and optimize and personalize endovascular treatments. Click here for a more complete description of this topic.

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Circle of Willis

cow

The purpose of this research was to construct patient-specific models of the circle of Willis of normal subjects. The objective is to better understand the distribution of flows in the circle of Willis and the alterations produced by temporary or permanent occlusion of the feeding vessels.

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Carotid Arteries

carot

The purpose of this research was to construct patient-specific models of healthy and diseased carotid arteries in order to better understand the hemodynamic significance of stenotic carotid arteries. The goal is to better assess the risk of stroke of patients with athersclerotic disease of the carotid arteries.

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Renal Arteries

renal

The purpose of this research was to model the hemodynamics in normal and diseased renal arteries. In particular, to estimate the pressure drop at stenosed renal arteries in order to better assess the hemodynamic significance of the stenosis. Validation studies of pressure drops across stenotic renal arteries were carried out with idealized in vitro models. Image Gallery:


Respiratory Airways

air

The purpose of this research was to model the airflow in the human respiratory airways in order to better understand the effect of respiratory diseases. Image Gallery:


Tumor Radiofrequency Ablation

rfa

The purpose of this research was to develop finite element methods for modeling the radio-frequency ablation of tumors in the presence of blood vessels. The objective is to integrate these models with image-guidance and treatment planning systems.

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Visualization

visu

The purpose of this research was to develop a distributed collaborative visualization system. This system, called zfem, contains several flow visualization techniques as well as volume rendering capabilities. It operates mainly on unstructured grids, and has been used in a wide range of CFD applications.

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Image Processing

imgs

The purpose of this research is to develop image processing methods for constructing patient-specific anatomical models from medical images. This involves: a) vessel detection algorithms, b) deformable models, c) level set methods, and d) construction of image-based arterial tree models.


Geometry Modeling

geom

The purpose of this research is to develop computational geometry algorithms to manipulate geometrical objects (surface triangulations) reconstructed from medical images in order to obtain surface descriptions suitable for unstructured grid generation. This includes: a) surface smoothing, b) surface merging or fusion, c) skeletonization, d) surface optimization, and e) interactive surface edition.


Meshing

mesh

The purpose of this research is to develop methods for generating unstructured volumetric grids suitable for CFD simulations directly from triangulated surfaces.

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Fluid-Structure Interaction

fsi

The purpose of this research is to develop methods to couple fluid and structural codes in order to simulate fluid-solid interactions. We focus on a loose coupling approach that combines independent fluid and solid codes with independent grids and time step sizes. This requires proper transfer of information between the codes and implicit coupling schemes for arbitrary time step sizes.

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Quick Links
Hemodynamics
Aneurysms
Circle of Willis
Carotids
Renals
Airways
RFA
Visualization
Image processing
Geometry modeling
Meshing
FSI